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Article Title |
Author(s) |
Type (Status) |
Available Online |
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In Vivo Dosimetry for Single-Fraction Targeted Intraoperative Radiotherapy (TARGIT) for Breast Cancer
DOI: 10.1016/j.ijrobp.2011.11.012
Purpose: In vivo dosimetry provides an independent check of delivered dose and gives confidence in the introduction or consistency of radiotherapy techniques. Single-fraction intraoperative radiothera...
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David J. Eaton,
Bronagh Best,
Chris Brew-Graves,
Stephen Duck,
Tabasom Ghaus,
Regina Gonzalez,
Katharine Pigott,
Claire Reynolds,
Norman R. Williams,
Mohammed R.S. Keshtgar
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Critical Appraisal of Acuros XB and Anisotropic Analytic Algorithm Dose Calculation in Advanced Non-Small-Cell Lung Cancer Treatments
DOI: 10.1016/j.ijrobp.2011.10.078
Purpose: To assess the clinical impact of the Acuros XB algorithm (implemented in the Varian Eclipse treatment-planning system) in non-small-cell lung cancer (NSCLC) cases. Methods and Materials: A CT...
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Antonella Fogliata,
Giorgia Nicolini,
Alessandro Clivio,
Eugenio Vanetti,
Luca Cozzi
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Decreased Risk of Radiation Pneumonitis with Incidental Concurrent Use of Angiotensin-Converting Enzyme Inhibitors and Thoracic Radiation Therapy
DOI: 10.1016/j.ijrobp.2011.11.013
Purpose: Angiotensin-converting enzyme (ACE) inhibitors have been shown to mitigate radiation-induced lung injury in preclinical models. The aim of this study was to evaluate whether ACE inhibitors de...
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Jordan Kharofa,
Eric P. Cohen,
Rade Tomic,
Qun Xiang,
Elizabeth Gore
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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MRI-based Preplanning Using CT and MRI Data Fusion in Patients with Cervical Cancer Treated with 3D-based Brachytherapy: Feasibility and Accuracy Study
DOI: 10.1016/j.ijrobp.2011.11.003
Purpose: Magnetic resonance imaging (MRI)-assisted radiation treatment planning enables enhanced target contouring. The purpose of this study is to analyze the feasibility and accuracy of computed tom...
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Martin Dolezel,
Karel Odrazka,
Jan Zizka,
Jaroslav Vanasek,
Tereza Kohlova,
Tomas Kroulik,
Dusan Spitzer,
Pavel Ryska,
Michal Tichy,
Milan Kostal,
Lubica Jalcova
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Quality Assurance of Multifractionated Pelvic Interstitial Brachytherapy for Postoperative Recurrences of Cervical Cancers: A Prospective Study
DOI: 10.1016/j.ijrobp.2011.11.018
Purpose: To evaluate three-dimensional needle displacements during multifractionated interstitial brachytherapy (BT) for cervical cancers. Methods and Materials: Patients scheduled to undergo pelvic i...
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Pragya Shukla,
Supriya Chopra,
Reena Engineer,
Umesh Mahantshetty,
Siji Nojin Paul,
Reena Phurailatpam,
Jamema SV,
Shyam K. Shrivastava
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Sexual Function and the Use of Medical Devices or Drugs to Optimize Potency after Prostate Brachytherapy
DOI: 10.1016/j.ijrobp.2011.11.004
Purpose: Prospective evaluation of sexual outcomes after prostate brachytherapy with iodine-125 seeds as monotherapy at a tertiary cancer care center. Methods and Materials: Subjects were 129 men with...
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J. Taylor Whaley,
Lawrence B. Levy,
David A. Swanson,
Thomas J. Pugh,
Rajat J. Kudchadker,
Teresa L. Bruno,
Steven J. Frank
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Outcome and Prognostic Factors in Endometrial Stromal Tumors: A Rare Cancer Network Study
DOI: 10.1016/j.ijrobp.2011.11.005
Purpose: To provide further understanding regarding outcome and prognostic factors of endometrial stromal tumors (EST). Methods and Materials: A retrospective analysis was performed on the records of ...
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Ulrike Schick,
Yasmin Bolukbasi,
Juliette Thariat,
Roxolyana Abdah-Bortnyak,
Abraham Kuten,
Sefik Igdem,
Hale Caglar,
Zeynep Ozsaran,
Kristina Lössl,
Ursula Schleicher,
Daniel Zwahlen,
Sylviane Villette,
Hansjörg Vees
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Sequence of Radiotherapy and Chemotherapy in Breast Cancer After Breast-Conserving Surgery
DOI: 10.1016/j.ijrobp.2011.11.020
Purpose: The optimal sequence of radiotherapy and chemotherapy in breast-conserving therapy is unknown. Methods and Materials: From 1983 through 2007, a total of 641 patients with 653 instances of bre...
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Jan J. Jobsen,
Job van der Palen,
Mariël Brinkhuis,
Francisca Ong,
Henk Struikmans
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Prognostic Value of Subclassification Using MRI in the T4 Classification Nasopharyngeal Carcinoma Intensity-Modulated Radiotherapy Treatment
DOI: 10.1016/j.ijrobp.2011.11.021
Purpose: To subclassify patients with the T4 classification nasopharyngeal carcinoma (NPC), according to the seventh edition of the American Joint Committee on Cancer staging system, using magnetic re...
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Lei Chen,
Li-Zhi Liu,
Mo Chen,
Wen-Fei Li,
Wen-Jing Yin,
Ai-Hua Lin,
Ying Sun,
Li Li,
Jun Ma
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Radiation Dose to the Brachial Plexus in Head-and-Neck Intensity-Modulated Radiation Therapy and Its Relationship to Tumor and Nodal Stage
DOI: 10.1016/j.ijrobp.2011.10.079
Purpose: The purpose of this retrospective study was to determine tumor factors contributing to brachial plexus (BP) dose in head-and-neck cancer (HNC) patients treated with intensity-modulated radiot...
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Minh Tam Truong,
Paul B. Romesser,
Muhammad M. Qureshi,
Nataliya Kovalchuk,
Lawrence Orlina,
John Willins
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Adjuvant Chemotherapy With or Without Pelvic Radiotherapy After Simultaneous Surgical Resection of Rectal Cancer with Liver Metastases: Analysis of Prognosis and Patterns of Recurrence
DOI: 10.1016/j.ijrobp.2011.10.070
Purpose: To investigate the outcomes of adjuvant chemotherapy (CT) or chemoradiotherapy (CRT) after simultaneous surgical resection in rectal cancer patients with liver metastases (LM). Materials and ...
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Ho Jung An,
Chang Sik Yu,
Sung-Cheol Yun,
Byung Woog Kang,
Yong Sang Hong,
Jae-Lyun Lee,
Min-Hee Ryu,
Heung Moon Chang,
Jin Hong Park,
Jong Hoon Kim,
Yoon-Koo Kang,
Jin Cheon Kim,
Tae Won Kim
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Intensity-Modulated Radiotherapy is Associated with Improved Global Quality of Life Among Long-Term Survivors of Head-and-Neck Cancer
DOI: 10.1016/j.ijrobp.2011.11.026
Purpose: To compare the long-term quality of life among patients treated with and without intensity-modulated radiotherapy (IMRT) for head-and-neck cancer. Methods and Materials: The University of Was...
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Allen M. Chen,
D. Gregory Farwell,
Quang Luu,
Esther G. Vazquez,
Derick H. Lau,
James A. Purdy
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Similar Survival with Breast Conservation Therapy or Mastectomy in the Management of Young Women with Early-Stage Breast Cancer
DOI: 10.1016/j.ijrobp.2011.10.075
Purpose: To evaluate survival outcomes of young women with early-stage breast cancer treated with breast conservation therapy (BCT) or mastectomy, using a large, population-based database. Methods and...
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Usama Mahmood,
Christopher Morris,
Geoffrey Neuner,
Matthew Koshy,
Susan Kesmodel,
Robert Buras,
Saranya Chumsri,
Ting Bao,
Katherine Tkaczuk,
Steven Feigenberg
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Effectiveness of Reirradiation for Painful Bone Metastases: A Systematic Review and Meta-Analysis
DOI: 10.1016/j.ijrobp.2011.10.080
Purpose: Reirradiation of painful bone metastases in nonresponders or patients with recurrent pain after initial response is performed in up to 42% of patients initially treated with radiotherapy. Lit...
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Merel Huisman,
Maurice A.A.J. van den Bosch,
Joost W. Wijlemans,
Marco van Vulpen,
Yvette M. van der Linden,
Helena M. Verkooijen
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Is Primary Prostate Cancer Treatment Influenced by Likelihood of Extraprostatic Disease? A Surveillance, Epidemiology and End Results Patterns of Care Study
DOI: 10.1016/j.ijrobp.2011.10.076
Purpose: To examine the patterns of primary treatment in a recent population-based cohort of prostate cancer patients, stratified by the likelihood of extraprostatic cancer as predicted by disease cha...
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Jordan A. Holmes,
Andrew Z. Wang,
Karen E. Hoffman,
Laura H. Hendrix,
Julian G. Rosenman,
William R. Carpenter,
Paul A. Godley,
Ronald C. Chen
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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The Number of High-Risk Factors and the Risk of Prostate Cancer–Specific Mortality After Brachytherapy: Implications for Treatment Selection
DOI: 10.1016/j.ijrobp.2011.11.023
Purpose: To determine whether an increasing number of high-risk factors is associated with higher prostate cancer–specific mortality (PCSM) among men treated with brachytherapy (BT)-based treatment, a...
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Daniel A. Wattson,
Ming-Hui Chen,
Judd W. Moul,
Brian J. Moran,
Daniel E. Dosoretz,
Cary N. Robertson,
Thomas J. Polascik,
Michelle H. Braccioforte,
Sharon A. Salenius,
Anthony V. D’Amico
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Predicting Rectal and Bladder Overdose During the Course of Prostate Radiotherapy Using Dose–Volume Data from Initial Treatment Fractions
DOI: 10.1016/j.ijrobp.2011.11.001
Purpose: To evaluate whether information from the initial fractions can determine which patients are likely to consistently exceed their planning dose–volume constraints during the course of radiother...
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Vedang Murthy,
Pragya Shukla,
Pranjal Adurkar,
Zubin Master,
Umesh Mahantshetty,
Shyamkishore Shrivastava
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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Long-Term Outcomes After High–Dose Postprostatectomy Salvage Radiation Treatment
DOI: 10.1016/j.ijrobp.2011.10.077
Purpose: To review the impact of high–dose radiotherapy (RT) in the postprostatectomy salvage setting on long-term biochemical control and distant metastases–free survival, and to identify clinical an...
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Anuj Goenka,
Juan Martin Magsanoc,
Xin Pei,
Michael Schechter,
Marisa Kollmeier,
Brett Cox,
Peter T. Scardino,
James A. Eastham,
Michael J. Zelefsky
et al.
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Full-length article
(In Press Corrected Proof)
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01 February 2012 |
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High-dose Helical Tomotherapy with Concurrent Full-dose Chemotherapy for Locally Advanced Pancreatic Cancer
DOI: 10.1016/j.ijrobp.2011.10.050
Purpose: To improve poor therapeutic outcome of current practice of chemoradiotherapy (CRT), high-dose helical tomotherapy (HT) with concurrent full-dose chemotherapy has been performed on patients wi...
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Jee Suk Chang,
Michael L.C. Wang,
Woong Sub Koom,
Hong In Yoon,
Yoonsun Chung,
Si Young Song,
Jinsil Seong
et al.
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Full-length article
(In Press Corrected Proof)
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30 January 2012 |
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Online Image-based Monitoring of Soft-tissue Displacements for Radiation Therapy of the Prostate
DOI: 10.1016/j.ijrobp.2011.10.049
Purpose: Emerging prolonged, hypofractionated radiotherapy regimens rely on high-dose conformality to minimize toxicity and thus can benefit from image guidance systems that continuously monitor targe...
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Jeffrey Schlosser,
Kenneth Salisbury,
Dimitre Hristov
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Projected Second Tumor Risk and Dose to Neurocognitive Structures After Proton Versus Photon Radiotherapy for Benign Meningioma
DOI: 10.1016/j.ijrobp.2011.10.056
Purpose: To calculated projected second tumor rates and dose to organs at risk (OAR) in patients with benign intracranial meningioma (BM), according to dosimetric comparisons between proton radiothera...
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Nils D. Arvold,
Andrzej Niemierko,
George P. Broussard,
Judith Adams,
Barbara Fullerton,
Jay S. Loeffler,
Helen A. Shih
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Evaluation of Field-in-Field Technique for Total Body Irradiation
DOI: 10.1016/j.ijrobp.2011.10.045
Purpose: To evaluate the clinical use of a field-in-field (FIF) technique for total body irradiation (TBI) using a treatment-planning system (TPS) and to verify TPS results with in vivo dose measureme...
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Cem Onal,
Aydan Sonmez,
Gungor Arslan,
Serhat Sonmez,
Esma Efe,
Ezgi Oymak
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Treatment Outcome of Medium-Dose-Rate Intracavitary Brachytherapy for Carcinoma of the Uterine Cervix: Comparison with Low-Dose-Rate Intracavitary Brachytherapy
DOI: 10.1016/j.ijrobp.2011.10.066
Purpose: To evaluate and compare the efficacy of medium-dose-rate (MDR) and low-dose-rate (LDR) intracavitary brachytherapy (ICBT) for uterine cervical cancer. Methods and Materials: We evaluated 419 ...
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Yuko Kaneyasu,
Midori Kita,
Tomohiko Okawa,
Katsuya Maebayashi,
Mari Kohno,
Tatsuo Sonoda,
Hisae Hirabayashi,
Yasushi Nagata,
Norio Mitsuhashi
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Is There an Additional Value of 11C-Choline PET-CT to T2-weighted MRI Images in the Localization of Intraprostatic Tumor Nodules?
DOI: 10.1016/j.ijrobp.2011.10.046
Purpose: To investigate the additional value of 11C-choline positron emission tomography (PET)-computed tomography (CT) to T2-weighted (T2w) magnetic resonance imaging (MRI) for localization of intrap...
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Laura Van den Bergh,
Michel Koole,
Sofie Isebaert,
Steven Joniau,
Christophe M. Deroose,
Raymond Oyen,
Evelyne Lerut,
Tom Budiharto,
Felix Mottaghy,
Guy Bormans,
Hendrik Van Poppel,
Karin Haustermans
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Analysis of Local Control in Patients Receiving IMRT for Resected Pancreatic Cancers
DOI: 10.1016/j.ijrobp.2011.08.026
Purpose: Intensity-modulated radiotherapy (IMRT) is increasingly incorporated into therapy for pancreatic cancer. A concern regarding this technique is the potential for geographic miss and decreased ...
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Susannah Yovino,
Bert W. Maidment,
Joseph M. Herman,
Naimish Pandya,
Olga Goloubeva,
Chris Wolfgang,
Richard Schulick,
Daniel Laheru,
Nader Hanna,
Richard Alexander,
William F. Regine
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Setup Variations in Radiotherapy of Anal Cancer: Advantages of Target Volume Reduction Using Image-Guided Radiation Treatment
DOI: 10.1016/j.ijrobp.2011.10.068
Purpose: To define setup variations in the radiation treatment (RT) of anal cancer and to report the advantages of image-guided RT (IGRT) in terms of reduction of target volume and treatment-related s...
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Yi-Jen Chen,
Steve Suh,
Rebecca A. Nelson,
An Liu,
Richard D. Pezner,
Jeffrey Y.C. Wong
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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TAT-Mediated Delivery of Tousled Protein to Salivary Glands Protects Against Radiation-Induced Hypofunction
DOI: 10.1016/j.ijrobp.2011.10.064
Purpose: Patients treated with radiotherapy for head-and-neck cancer invariably suffer its deleterious side effect, xerostomia. Salivary hypofunction ensuing from the irreversible destruction of gland...
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Gulshan Sunavala-Dossabhoy,
Senthilnathan Palaniyandi,
Charles Richardson,
Arrigo De Benedetti,
Lisa Schrott,
Gloria Caldito
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Role of Early Postradiation Magnetic Resonance Imaging Scans in Children with Diffuse Intrinsic Pontine Glioma
DOI: 10.1016/j.ijrobp.2011.09.046
Purpose: To determine optimal timing of assessing postradiation radiographic response on magnetic resonance imaging (MRI) scans in pediatric patients with diffuse intrinsic pontine glioma (DIPG). Meth...
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Christine Ko,
Aradhana Kaushal,
Dima A. Hammoud,
Emilie A. Steffen-Smith,
Robyn Bent,
Deborah Citrin,
Kevin Camphausen,
Katherine E. Warren
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Lhermitte Sign After Chemo-IMRT of Head-and-Neck Cancer: Incidence, Doses, and Potential Mechanisms
DOI: 10.1016/j.ijrobp.2011.10.052
Purpose: We have observed a higher rate of Lhermitte sign (LS) after chemo–intensity-modulated radiotherapy (IMRT) of head-and-neck cancer than the published rates after conventional radiotherapy. We ...
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Daniel Pak,
Karen Vineberg,
Felix Feng,
Randall K. Ten Haken,
Avraham Eisbruch
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Comparison of Heart and Coronary Artery Doses Associated with Intensity-Modulated Radiotherapy Versus Three-Dimensional Conformal Radiotherapy for Distal Esophageal Cancer
DOI: 10.1016/j.ijrobp.2011.10.053
Purpose: To compare heart and coronary artery radiation exposure using intensity-modulated radiotherapy (IMRT) vs. four-field three-dimensional conformal radiotherapy (3D-CRT) treatment plans for pati...
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Thomas P. Kole,
Osarhieme Aghayere,
Jason Kwah,
Ellen D. Yorke,
Karyn A. Goodman
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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A Computational Model of Cellular Response to Modulated Radiation Fields
DOI: 10.1016/j.ijrobp.2011.10.058
Purpose: To develop a model to describe the response of cell populations to spatially modulated radiation exposures of relevance to advanced radiotherapies. Materials and Methods: A Monte Carlo model ...
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Stephen J. McMahon,
Karl T. Butterworth,
Conor K. McGarry,
Colman Trainor,
Joe M. O’Sullivan,
Alan R. Hounsell,
Kevin M. Prise
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Glioblastoma Treatment: Bypassing the Toxicity of Platinum Compounds by Using Liposomal Formulation and Increasing Treatment Efficiency with Concomitant Radiotherapy
DOI: 10.1016/j.ijrobp.2011.10.054
Purpose: Treatments of glioblastoma with cisplatin or oxaliplatin only marginally improve the overall survival of patients and cause important side effects. To prevent adverse effects, improve deliver...
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Gabriel Charest,
Léon Sanche,
David Fortin,
David Mathieu,
Benoit Paquette
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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High-Dose-Rate Brachytherapy and External-Beam Radiotherapy for Hormone-Naïve Low- and Intermediate-Risk Prostate Cancer: A 7-Year Experience
DOI: 10.1016/j.ijrobp.2011.10.055
Purpose: To report clinical outcomes and early and late complications in 264 hormone-naïve patients with low- and intermediate-risk prostate cancer treated with high-dose-rate brachytherapy (HDR-BT) i...
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Shafak Aluwini,
Peter H. van Rooij,
Wim J. Kirkels,
Peter P. Jansen,
John O. Praag,
Chris H. Bangma,
Inger-Karine K. Kolkman-Deurloo
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Personalized Assessment of kV Cone Beam Computed Tomography Doses in Image-guided Radiotherapy of Pediatric Cancer Patients
DOI: 10.1016/j.ijrobp.2011.10.072
Purpose: To develop a quantitative method for the estimation of kV cone beam computed tomography (kVCBCT) doses in pediatric patients undergoing image-guided radiotherapy. Methods and Materials: Forty...
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Yibao Zhang,
Yulong Yan,
Ravinder Nath,
Shanglian Bao,
Jun Deng
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Pretreatment Staging Positron Emission Tomography/Computed Tomography in Patients With Inflammatory Breast Cancer Influences Radiation Treatment Field Designs
DOI: 10.1016/j.ijrobp.2011.10.040
Purpose: Positron emission tomography/computed tomography (PET/CT) is increasingly being utilized for staging of inflammatory breast cancer (IBC). The purpose of this study was to define how pretreatm...
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Gary V. Walker,
Naoki Niikura,
Wei Yang,
Eric Rohren,
Vicente Valero,
Wendy A. Woodward,
Ricardo H. Alvarez,
Anthony Lucci,
Naoto T. Ueno,
Thomas A. Buchholz
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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Frameless Angiogram-Based Stereotactic Radiosurgery for Treatment of Arteriovenous Malformations
DOI: 10.1016/j.ijrobp.2011.10.044
Purpose: Stereotactic radiosurgery (SRS) is an effective alternative to microsurgical resection or embolization for definitive treatment of arteriovenous malformations (AVMs). Digital subtraction angi...
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Xing-Qi Lu,
Anand Mahadevan,
George Mathiowitz,
Pei-Jan P. Lin,
Ajith Thomas,
Ekkehard M. Kasper,
Scott R. Floyd,
Edward Holupka,
Salvatore La Rosa,
Frank Wang,
Mary Ann Stevenson
et al.
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Full-length article
(In Press Corrected Proof)
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27 January 2012 |
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The Impact of Brachytherapy on Prostate Cancer–Specific Mortality for Definitive Radiation Therapy of High-Grade Prostate Cancer: A Population-Based Analysis
DOI: 10.1016/j.ijrobp.2011.09.055
Purpose: This population-based analysis compared prostate cancer–specific mortality (PCSM) in a cohort of patients with high-risk prostate cancer after nonsurgical treatment with external beam radiati...
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Xinglei Shen,
Scott W. Keith,
Mark V. Mishra,
Adam P. Dicker,
Timothy N. Showalter
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Applying a Hypoxia-Incorporating TCP Model to Experimental Data on Rat Sarcoma
DOI: 10.1016/j.ijrobp.2011.10.015
Purpose: To verify whether a tumor control probability (TCP) model which mechanistically incorporates acute and chronic hypoxia is able to describe animal in vivo dose–response data, exhibiting tumor ...
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Ruggero Ruggieri,
Nadejda Stavreva,
Stefania Naccarato,
Pavel Stavrev
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Monochromatic Minibeams Radiotherapy: From Healthy Tissue-sparing Effect Studies Toward First Experimental Glioma Bearing Rats Therapy
DOI: 10.1016/j.ijrobp.2011.09.013
Purpose: The purpose of this study was to evaluate high-dose single fraction delivered with monochromatic X-rays minibeams for the radiotherapy of primary brain tumors in rats. Methods and Materials: ...
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Pierre Deman,
Mathias Vautrin,
Magali Edouard,
Vasile Stupar,
Laure Bobyk,
Régine Farion,
Hélène Elleaume,
Chantal Rémy,
Emmanuel L. Barbier,
François Estève,
Jean-François Adam
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Image-guided Radiotherapy for Left-sided Breast Cancer Patients: Geometrical Uncertainty of the Heart
DOI: 10.1016/j.ijrobp.2011.08.024
Purpose: To quantify the geometrical uncertainties for the heart during radiotherapy treatment of left-sided breast cancer patients and to determine and validate planning organ at risk volume (PRV) ma...
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Rajko Topolnjak,
Gerben R. Borst,
Jasper Nijkamp,
Jan-Jakob Sonke
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Individualized Nonadaptive and Online-Adaptive Intensity-Modulated Radiotherapy Treatment Strategies for Cervical Cancer Patients Based on Pretreatment Acquired Variable Bladder Filling Computed Tomography Scans
DOI: 10.1016/j.ijrobp.2011.10.011
Purpose: To design and evaluate individualized nonadaptive and online-adaptive strategies based on a pretreatment established motion model for the highly deformable target volume in cervical cancer pa...
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M.L. Bondar,
M.S. Hoogeman,
J.W. Mens,
S. Quint,
R. Ahmad,
G. Dhawtal,
B.J. Heijmen
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Optimized Planning Target Volume for Intact Cervical Cancer
DOI: 10.1016/j.ijrobp.2011.10.027
Purpose: To model interfraction clinical target volume (CTV) variation in patients with intact cervical cancer and design a planning target volume (PTV) that minimizes normal tissue dose while maximiz...
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Alvin Khan,
Lindsay G. Jensen,
Shuai Sun,
William Y. Song,
Catheryn M. Yashar,
Arno J. Mundt,
Fu-quan Zhang,
Steve B. Jiang,
Loren K. Mell
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Prostate Brachytherapy with Oblique Needles to Treat Large Glands and Overcome Pubic Arch Interference
DOI: 10.1016/j.ijrobp.2011.10.012
Purpose: First, to show that low-dose-rate prostate brachytherapy plans using oblique needle trajectories are more successful than parallel trajectories for large prostates with pubic arch interferenc...
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Bon Ryu,
Jeff Bax,
Chandima Edirisinge,
Craig Lewis,
Jeff Chen,
David D’Souza,
Aaron Fenster,
Eugene Wong
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Correlation Between Radiation Dose to 18F-FDG-PET Defined Active Bone Marrow Subregions and Acute Hematologic Toxicity in Cervical Cancer Patients Treated with Chemoradiotherapy
DOI: 10.1016/j.ijrobp.2011.09.048
Purpose: To test the hypothesis that radiation dose to 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET)-defined active bone marrow (BMACT) subregions is correlated with hematologic to...
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Brent S. Rose,
Yun Liang,
Steven K. Lau,
Lindsay G. Jensen,
Catheryn M. Yashar,
Carl K. Hoh,
Loren K. Mell
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Oxidative Stress Mediates Radiation Lung Injury by Inducing Apoptosis
DOI: 10.1016/j.ijrobp.2011.08.005
Purpose: Apoptosis in irradiated normal lung tissue has been observed several weeks after radiation. However, the signaling pathway propagating cell death after radiation remains unknown. Methods and ...
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Yu Zhang,
Xiuwu Zhang,
Zahid N. Rabbani,
Isabel L. Jackson,
Zeljko Vujaskovic
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Resected Pancreatic Neuroendocrine Tumors: Patterns of Failure and Disease-Related Outcomes With or Without Radiotherapy
DOI: 10.1016/j.ijrobp.2011.09.041
Purpose: Pancreatic neuroendocrine tumors (NET) are rare and have better disease-related outcomes compared with pancreatic adenocarcinoma. Surgical resection remains the standard of care, although man...
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Timothy M. Zagar,
Rebekah R. White,
Christopher G. Willett,
Douglas S. Tyler,
Paulie Papavassiliou,
Katia T. Papalezova,
Cynthia D. Guy,
Gloria Broadwater,
Robert W. Clough,
Brian G. Czito
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Risk of Developing Cardiovascular Disease after Involved Node Radiotherapy versus Mantle Field for Hodgkin Lymphoma
DOI: 10.1016/j.ijrobp.2011.09.020
Purpose: Hodgkin lymphoma (HL) survivors are known to have increased cardiac mortality and morbidity. The risk of developing cardiovascular disease after involved node radiotherapy (INRT) is currently...
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Maja V. Maraldo,
Nils Patrik Brodin,
Ivan R. Vogelius,
Marianne C. Aznar,
Per Munck af Rosenschöld,
Peter M. Petersen,
Lena Specht
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head-and-Neck Cancer Outcomes
DOI: 10.1016/j.ijrobp.2011.10.022
Purpose: We previously showed that metabolic tumor volume (MTV) on positron emission tomography—computed tomography (PET-CT) predicts for disease recurrence and death in head-and-neck cancer (HNC). We...
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Karen P. Chu,
James D. Murphy,
Trang H. La,
Trevor E. Krakow,
Andrei Iagaru,
Edward E. Graves,
Annie Hsu,
Peter G. Maxim,
Billy Loo,
Daniel T. Chang,
Quynh-Thu Le
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Patterns of Radiotherapy Practice for Patients with Cervical Cancer in Japan, 2003–2005: Changing Trends in the Pattern of Care Process
DOI: 10.1016/j.ijrobp.2011.10.013
Purpose: The patterns of care study (PCS) of radiotherapy for cervical cancer in Japan over the last 10 years was reviewed. Methods and Materials: The Japanese PCS working group analyzed data from 1,2...
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Natsuo Tomita,
Takafumi Toita,
Takeshi Kodaira,
Atsunori Shinoda,
Takashi Uno,
Hodaka Numasaki,
Teruki Teshima,
Michihide Mitsumori
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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po2 Fluctuation Pattern and Cycling Hypoxia in Human Cervical Carcinoma and Melanoma Xenografts
DOI: 10.1016/j.ijrobp.2011.09.037
Purpose: Blood perfusion in tumors is spatially and temporally heterogeneous, resulting in local fluctuations in tissue oxygen tension (po2) and tissue regions showing cycling hypoxia. In this study, ...
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Christine Ellingsen,
Kirsti Marie Øvrebø,
Kanthi Galappathi,
Berit Mathiesen,
Einar K. Rofstad
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Effect of Statins and Anticoagulants on Prostate Cancer Aggressiveness
DOI: 10.1016/j.ijrobp.2011.09.042
Purpose: Statins and anticoagulants (ACs) have both been associated with a less-aggressive prostate cancer (PCa) and a better outcome after treatment of localized PCa. The results of these studies mig...
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Moein Alizadeh,
Marie-Pierre Sylvestre,
Thomas Zilli,
Thu Van Nguyen,
Jean-Pierre Guay,
Jean-Paul Bahary,
Daniel Taussky
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Validation that Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer
DOI: 10.1016/j.ijrobp.2011.10.023
Purpose: We have previously reported that metabolic tumor volume (MTV) obtained from pretreatment 18F-fluorodeoxydeglucose positron emission tomography (FDG PET)/ computed tomography (CT) predicted ou...
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Chad Tang,
James D. Murphy,
Brian Khong,
Trang H. La,
Christina Kong,
Nancy J. Fischbein,
A. Dimitrios Colevas,
Andrei H. Iagaru,
Edward E. Graves,
Billy W. Loo,
Quynh-Thu Le
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Long-Term Results of Conformal Radiotherapy for Progressive Airway Amyloidosis
DOI: 10.1016/j.ijrobp.2011.07.036
Purpose: To evaluate the efficacy of conformal external beam radiotherapy (RT) for local control of progressive airway amyloidosis. Methods and Materials: We conducted a retrospective review of patien...
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Minh Tam Truong,
Lisa A. Kachnic,
Gregory A. Grillone,
Harry K. Bohrs,
Richard Lee,
Osamu Sakai,
John L. Berk
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Postoperative Radiotherapy in Prostate Cancer: The Case of the Missing Target
DOI: 10.1016/j.ijrobp.2011.09.039
Purpose: Postoperative radiotherapy (XRT) increases survival in high-risk prostate cancer patients. Approximately 50% of patients on long-term follow-up relapse despite adjuvant XRT and the predominan...
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Jennifer Croke,
Shawn Malone,
Nicolas Roustan Delatour,
Eric Belanger,
Leonard Avruch,
Christopher Morash,
Cathleen Kayser,
Kathryn Underhill,
Johanna Spaans
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Comparison of Three-Dimensional (3D) Conformal Proton Radiotherapy (RT), 3D Conformal Photon RT, and Intensity-Modulated RT for Retroperitoneal and Intra-Abdominal Sarcomas
DOI: 10.1016/j.ijrobp.2011.10.014
Purpose: To compare three-dimensional conformal proton radiotherapy (3DCPT), intensity-modulated photon radiotherapy (IMRT), and 3D conformal photon radiotherapy (3DCRT) to predict the optimal RT tech...
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Erika L. Swanson,
Daniel J. Indelicato,
Debbie Louis,
Stella Flampouri,
Zuofeng Li,
Christopher G. Morris,
Nitesh Paryani,
Roelf Slopsema
et al.
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Full-length article
(In Press Corrected Proof)
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23 January 2012 |
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Can Drugs Enhance Hypofractionated Radiotherapy? A Novel Method of Modeling Radiosensitization Using In Vitro Data
DOI: 10.1016/j.ijrobp.2011.06.1990
Purpose: Hypofractionated radiotherapy (hRT) is being explored for a number of malignancies. The potential benefit of giving concurrent chemotherapy with hRT is not known. We sought to predict the eff...
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Nitin Ohri,
Adam P. Dicker,
Yaacov Richard Lawrence
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Full-length article
(In Press Corrected Proof)
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19 January 2012 |
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How do the ASTRO Consensus Statement Guidelines for the Application of Accelerated Partial Breast Irradiation Fit Intraoperative Radiotherapy? A Retrospective Analysis of Patients Treated at the European Institute of Oncology
DOI: 10.1016/j.ijrobp.2011.08.014
Purpose: To verify how the classification according to the American Society for Therapeutic Radiation Oncology (ASTRO) consensus statement (CS) for the application of accelerated partial breast irradi...
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Maria Cristina Leonardi,
Patrick Maisonneuve,
Mauro Giuseppe Mastropasqua,
Anna Morra,
Roberta Lazzari,
Nicole Rotmensz,
Claudia Sangalli,
Alberto Luini,
Umberto Veronesi,
Roberto Orecchia
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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How Effective are Clinical Pathways with and Without Online Peer-Review? An Analysis of Bone Metastases Pathway in a Large, Integrated National Cancer Institute–Designated Comprehensive Cancer Center Network
DOI: 10.1016/j.ijrobp.2011.09.056
Purpose: Clinical pathways are an important tool used to manage the quality in health care by standardizing processes. This study evaluated the impact of the implementation of a peer-reviewed clinical...
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Sushil Beriwal,
Malolan S. Rajagopalan,
John C. Flickinger,
Susan M. Rakfal,
Edwin Rodgers,
Dwight E. Heron
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Electron Irradiation of Conjunctival Lymphoma—Monte Carlo Simulation of the Minute Dose Distribution and Technique Optimization
DOI: 10.1016/j.ijrobp.2011.09.014
Purpose: External beam radiotherapy is the only conservative curative approach for Stage I non-Hodgkin lymphomas of the conjunctiva. The target volume is geometrically complex because it includes the ...
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Lorenzo Brualla,
Francisco J. Zaragoza,
Josep Sempau,
Andrea Wittig,
Wolfgang Sauerwein
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |
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Predicting the Risk of Secondary Lung Malignancies Associated with Whole-Breast Radiation Therapy
DOI: 10.1016/j.ijrobp.2011.09.052
Purpose: The risk of secondary lung malignancy (SLM) is a significant concern for women treated with whole-breast radiation therapy after breast-conserving surgery for early-stage breast cancer. In th...
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John Ng,
Igor Shuryak,
Yanguang Xu,
K.S. Clifford Chao,
David J. Brenner,
Ryan J. Burri
et al.
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Full-length article
(In Press Corrected Proof)
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16 January 2012 |