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Issue Highlights page A21 Full Text | Full-Text PDF (30 KB)
Editorials
The Ethics of Hypofractionation for Prostate Cancer W. Robert Lee pages 969-970 Full Text | Full-Text PDF (61 KB)
Histologic Response Grading After Chemoradiation in Locally Advanced Rectal Cancer: A Proposal for Standardized Reporting Rob Glynne-Jones, Nicola Anyemene pages 971-973 Full Text | Full-Text PDF (77 KB)
Mentors, Mensches, and Models Todd H. Wasserman, C. Norman Coleman pages 974-975 Full Text | Full-Text PDF (64 KB)
Rapid Communication
Major Vault Protein May Affect Nonhomologous End-Joining Repair and Apoptosis Through Ku70/80 and BAX Downregulation in Cervical Carcinoma Tumors Marta Lloret, Pedro Carlos Lara, Elisa Bordón, Fausto Fontes, Agustin Rey, Beatriz Pinar, Orlando Falcón pages 976-979 Abstract | Full Text | Full-Text PDF (198 KB)
Critical Reviews
Radiation-Induced Cardiac Toxicity After Therapy for Breast Cancer: Interaction Between Treatment Era and Follow-Up Duration Senem Demirci, Jiho Nam, Jessica L. Hubbs, Thu Nguyen, Lawrence B. Marks pages 980-987 Abstract | Full Text | Full-Text PDF (170 KB)
On the Path to Seeking Novel Radiosensitizers David Katz, Emma Ito, Fei-Fei Liu pages 988-996 Abstract | Full Text | Full-Text PDF (332 KB)
Reports
ACR Appropriateness Criteria® on Postmastectomy Radiotherapy: Expert Panel on Radiation Oncology—Breast Marie E. Taylor, Bruce G. Haffty, Rachel Rabinovitch, Douglas W. Arthur, Francine E. Halberg, Eric A. Strom, Julia R. White, Melody A. Cobleigh, Stephen B. Edge pages 997-1002 Abstract | Full Text | Full-Text PDF (110 KB)
An Increase in Medical Student Knowledge of Radiation Oncology: A Pre–Post Examination Analysis of the Oncology Education Initiative Ariel E. Hirsch, Pauline Mulleady Bishop, Luqman Dad, Deeptej Singh, Priscilla J. Slanetz pages 1003-1008.e2 Abstract | Full Text | Full-Text PDF (436 KB)
Clinical Investigations
Prostate
Achieving an Undetectable PSA After Radiotherapy for Biochemical Progression After Radical Prostatectomy Is an Independent Predictor of Biochemical Outcome—Results of a Retrospective Study, 28 October 2008 Thomas Wiegel, Gunnar Lohm, Dirk Bottke, Stefan Höcht, Kurt Miller, Alessandra Siegmann, Martin Schostak, Konrad Neumann, Wolfgang Hinkelbein pages 1009-1016 Abstract | Full Text | Full-Text PDF (216 KB)
Obesity and Risk of Biochemical Failure for Patients Receiving Salvage Radiotherapy After Prostatectomy, 15 August 2008 Christopher R. King, Michael T. Spiotto, Daniel S. Kapp pages 1017-1022 Abstract | Full Text | Full-Text PDF (147 KB)
Predictive Factors for Acute and Late Urinary Toxicity After Permanent Prostate Brachytherapy: Long-Term Outcome in 712 Consecutive Patients, 25 December 2008 Mira Keyes, Stacy Miller, Veronika Moravan, Tom Pickles, Michael McKenzie, Howard Pai, Mitchell Liu, Winkle Kwan, Alexander Agranovich, Ingrid Spadinger, Vincent Lapointe, Ross Halperin, W. James Morris pages 1023-1032 Abstract | Full Text | Full-Text PDF (376 KB)
Prognostic Value of Survivin in Locally Advanced Prostate Cancer: Study Based on RTOG 8610, 31 October 2008 Min Zhang, Alex Ho, Elizabeth H. Hammond, Yoshiyuki Suzuki, R. Scott Bermudez, R. Jeffrey Lee, Michael Pilepich, William U. Shipley, Howard Sandler, Li-Yan Khor, Alan Pollack, Arnab Chakravarti pages 1033-1042 Abstract | Full Text | Full-Text PDF (316 KB)
Stereotactic Body Radiotherapy for Localized Prostate Cancer: Interim Results of a Prospective Phase II Clinical Trial, 27 August 2008 Christopher R. King, James D. Brooks, Harcharan Gill, Todd Pawlicki, Cristian Cotrutz, Joseph C. Presti pages 1043-1048 Abstract | Full Text | Full-Text PDF (145 KB)
Breast
Analysis of Factors Associated With Radiation-Induced Bronchiolitis Obliterans Organizing Pneumonia Syndrome After Breast-Conserving Therapy, 27 August 2008 Norihisa Katayama, Shuhei Sato, Kuniaki Katsui, Mitsuhiro Takemoto, Toshihide Tsuda, Atsushi Yoshida, Tsuneharu Morito, Tomio Nakagawa, Akifumi Mizuta, Takahiro Waki, Harutaka Niiya, Susumu Kanazawa pages 1049-1054 Abstract | Full Text | Full-Text PDF (106 KB)
Outcomes After Breast Conservation Treatment With Radiation in Women With Prior Nonbreast Malignancy and Subsequent Invasive Breast Carcinoma, 17 October 2008 Deepika Nemani, Neha Vapiwala, Wei-Ting Hwang, Lawrence J. Solin pages 1055-1060 Abstract | Full Text | Full-Text PDF (146 KB)
Estimating Cardiac Exposure From Breast Cancer Radiotherapy in Clinical Practice, 29 October 2008 C.W. Taylor, P. McGale, J.M. Povall, E. Thomas, S. Kumar, D. Dodwell, S.C. Darby pages 1061-1068 Abstract | Full Text | Full-Text PDF (1285 KB)
Brain
Motexafin Gadolinium Combined With Prompt Whole Brain Radiotherapy Prolongs Time to Neurologic Progression in Non–Small-Cell Lung Cancer Patients With Brain Metastases: Results of a Phase III Trial, 31 October 2008 Minesh P. Mehta, William R. Shapiro, See C. Phan, Radj Gervais, Christian Carrie, Pierre Chabot, Roy A. Patchell, Michael J. Glantz, Lawrence Recht, Corey Langer, Ranjan K. Sur, Wilson H. Roa, Marc A. Mahe, Andre Fortin, Carsten Nieder, Christina A. Meyers, Jennifer A. Smith, Richard A. Miller, Markus F. Renschler pages 1069-1076 Abstract | Full Text | Full-Text PDF (268 KB)
A Matched-Pair Analysis Comparing Whole-Brain Radiotherapy Plus Stereotactic Radiosurgery Versus Surgery Plus Whole-Brain Radiotherapy and a Boost to the Metastatic Site for One or Two Brain Metastases, 15 August 2008 Dirk Rades, Jan-Dirk Kueter, Andre Pluemer, Theo Veninga, Steven E. Schild pages 1077-1081 Abstract | Full Text | Full-Text PDF (187 KB)
Dose-Dependent Effects of Radiation Therapy on Cerebral Blood Flow, Metabolism, and Neurocognitive Dysfunction, 27 August 2008 Carol A. Hahn, Su-Min Zhou, Renee Raynor, Andrea Tisch, Kim Light, Timothy Shafman, Terence Wong, John Kirkpatrick, Timothy Turkington, Donna Hollis, Lawrence B. Marks pages 1082-1087 Abstract | Full Text | Full-Text PDF (210 KB)
Head and Neck
Impact of Adding Concomitant Chemotherapy to Hyperfractionated Accelerated Radiotherapy for Advanced Head-and-Neck Squamous Cell Carcinoma, 15 August 2008 Sandra Nuyts, Piet Dirix, Paul M.J. Clement, Vincent Vander Poorten, Pierre Delaere, Joseph Schoenaers, Robert Hermans, Walter Van den Bogaert pages 1088-1095 Abstract | Full Text | Full-Text PDF (265 KB)
Intensity-Modulated Radiotherapy in Postoperative Treatment of Oral Cavity Cancers, 15 August 2008 Daniel R. Gomez, Joanne E. Zhung, Jennifer Gomez, Kelvin Chan, Abraham J. Wu, Suzanne L. Wolden, David G. Pfister, Ashok Shaha, Jatin P. Shah, Dennis H. Kraus, Richard J. Wong, Nancy Y. Lee pages 1096-1103 Abstract | Full Text | Full-Text PDF (274 KB)
Total Microvessel Perimeter Per Tumor Area Is a Predictor of Radiosensitivity in Early-Stage Glottic Carcinoma, 23 October 2008 Shichuan Zhang, Ryuichi Hayashi, Masato Fujii, Yasuhisa Hasegawa, Kunitoshi Yoshino, Masashi Fukayama, Atsushi Ochiai pages 1104-1109 Abstract | Full Text | Full-Text PDF (1415 KB)
Truths and Myths About Radiotherapy for Verrucous Carcinoma of Larynx, 15 August 2008 Shao Hui Huang, Gina Lockwood, Jonathan Irish, Jolie Ringash, Bernard Cummings, John Waldron, John Kim, Laura A. Dawson, Andrew Bayley, Andrew Hope, Brian O'Sullivan pages 1110-1115 Abstract | Full Text | Full-Text PDF (147 KB)
Pediatric and Young Adult Nasopharyngeal Carcinoma Patients Treated With Preradiation Cisplatin and Docetaxel Chemotherapy, 10 September 2008 Ali Varan, Enis Özyar, Funda Çorapçioğlu, Yavuz Köksal, Burça Aydin, Nalan Yazici, Canan Akyüz, Münevver Büyükpamukçu pages 1116-1120 Abstract | Full Text | Full-Text PDF (111 KB)
Major Late Toxicities After Conformal Radiotherapy for Nasopharyngeal Carcinoma—Patient- and Treatment-Related Risk Factors, 26 August 2008 Anne W.M. Lee, W.T. Ng, W.M. Hung, C.W. Choi, Raymond Tung, Y.H. Ling, Peter T.C. Cheng, T.K. Yau, Amy T.Y. Chang, Samuel K.C. Leung, Michael C.H. Lee, Soren M. Bentzen pages 1121-1128 Abstract | Full Text | Full-Text PDF (277 KB)
Aichi Cancer Center Initial Experience of Intensity Modulated Radiation Therapy for Nasopharyngeal Cancer Using Helical Tomotherapy, 14 October 2008 Takeshi Kodaira, Natsuo Tomita, Hiroyuki Tachibana, Tatsuya Nakamura, Rie Nakahara, Haruo Inokuchi, Nobukazu Fuwa pages 1129-1134 Abstract | Full Text | Full-Text PDF (1414 KB)
Assessment of Tumor Volumes in Skull Base Glomus Tumors Using Gluc-Lys[18F]-TOCA Positron Emission Tomography, 10 September 2008 Sabrina T. Astner, Ralph A. Bundschuh, Ambros J. Beer, Sibylle I. Ziegler, Bernd J. Krause, Markus Schwaiger, Michael Molls, Anca L. Grosu, Markus Essler pages 1135-1140 Abstract | Full Text | Full-Text PDF (570 KB)
Cervix
Intestinal Malabsorption in Long-Term Survivors of Cervical Cancer Treated With Radiotherapy, 29 August 2008 Ingvild Vistad, Gunnar B. Kristensen, Sophie D. Fosså, Alv A. Dahl, Lars Mørkrid pages 1141-1147 Abstract | Full Text | Full-Text PDF (209 KB)
Pancreas
CA 19-9 as a Predictor for Response and Survival in Advanced Pancreatic Cancer Patients Treated With Chemoradiotherapy, 29 August 2008 Woong Sub Koom, Jinsil Seong, Yong Bae Kim, Hae Ok Pyun, Si Young Song pages 1148-1154 Abstract | Full Text | Full-Text PDF (216 KB)
Liver
The Treatment Responses in Cases of Radiation Therapy to Portal Vein Thrombosis in Advanced Hepatocellular Carcinoma, 29 August 2008 Yu-Jie Huang, Hsuan-Chih Hsu, Chang-Yu Wang, Chong-Jong Wang, Hui-Chun Chen, Eng-Yen Huang, Fu-Min Fang, Sheng-Nan Lu pages 1155-1163 Abstract | Full Text | Full-Text PDF (302 KB)
Children
Hyperparathyroidism After Irradiation for Childhood Malignancy, 09 September 2008 Todd McMullen, Greg Bodie, Anthony Gill, Catharina Ihre-Lundgren, Albert Shun, Mary Bergin, Graham Stevens, Leigh Delbridge pages 1164-1168 Abstract | Full Text | Full-Text PDF (265 KB)
Palliation
Recursive Partitioning Analysis of Prognostic Factors for Survival in Patients With Advanced Cancer, 20 October 2008 Edward Chow, Mohamed Abdolell, Tony Panzarella, Kristin Harris, Andrea Bezjak, Padraig Warde, Ian Tannock pages 1169-1176 Abstract | Full Text | Full-Text PDF (324 KB)
Biology Contributions
Immunohistochemical Detection of Changes in Tumor Hypoxia James Russell, Sean Carlin, Sean A. Burke, Bixiu Wen, Kwang Mo Yang, C. Clifton Ling pages 1177-1186 Abstract | Full Text | Full-Text PDF (1430 KB)
Acute Normal Tissue Reactions in Head-and-Neck Cancer Patients Treated With IMRT: Influence of Dose and Association With Genetic Polymorphisms in DNA DSB Repair Genes Joke Werbrouck, Kim De Ruyck, Fréderic Duprez, Liv Veldeman, Kathleen Claes, Marc Van Eijkeren, Tom Boterberg, Petra Willems, Anne Vral, Wilfried De Neve, Hubert Thierens pages 1187-1195 Abstract | Full Text | Full-Text PDF (303 KB)
Peroxiredoxin IV Protects Cells From Radiation-Induced Apoptosis in Head-and-Neck Squamous Cell Carcinoma Jung Je Park, Hyo Won Chang, Eun-Jeong Jeong, Jong-Lyel Roh, Seung-Ho Choi, Sea-Yuong Jeon, Gyung Hyuck Ko, Sang Yoon Kim pages 1196-1202 Abstract | Full Text | Full-Text PDF (435 KB)
Physical, Heritable and Age-Related Factors as Modifiers of Radiation Cancer Risk in Patched Heterozygous Mice, 09 February 2009 Simonetta Pazzaglia, Emanuela Pasquali, Mirella Tanori, Mariateresa Mancuso, Simona Leonardi, Vincenzo di Majo, Simonetta Rebessi, Anna Saran pages 1203-1210 Abstract | Full Text | Full-Text PDF (420 KB)
Diversity and Complexity of Ceramide Generation After Exposure of Jurkat Leukemia Cells to Irradiation Dominique Ardail, Mira Maalouf, Anthony Boivin, Olivier Chapet, Jacques Bodennec, Robert Rousson, Claire Rodriguez-Lafrasse pages 1211-1218 Abstract | Full Text | Full-Text PDF (368 KB)
Inhibition of 4E-BP1 Sensitizes U87 Glioblastoma Xenograft Tumors to Irradiation by Decreasing Hypoxia Tolerance Ludwig Dubois, Michaël G. Magagnin, Arjen H.G. Cleven, Sherry A. Weppler, Beat Grenacher, Willy Landuyt, Natasja Lieuwes, Philippe Lambin, Thomas A. Gorr, Marianne Koritzinsky, Bradly G. Wouters pages 1219-1227 Abstract | Full Text | Full-Text PDF (362 KB) | Add-Ons
Physics Contributions
Using Fluorodeoxyglucose Positron Emission Tomography to Assess Tumor Volume During Radiotherapy for Non–Small-Cell Lung Cancer and Its Potential Impact on Adaptive Dose Escalation and Normal Tissue Sparing Mary Feng, Feng-Ming Kong, Milton Gross, Shaneli Fernando, James A. Hayman, Randall K. Ten Haken pages 1228-1234 Abstract | Full Text | Full-Text PDF (1905 KB)
Dosimetric Evaluation of Heterogeneity Corrections for RTOG 0236: Stereotactic Body Radiotherapy of Inoperable Stage I-II Non–Small-Cell Lung Cancer Ying Xiao, Lech Papiez, Rebecca Paulus, Robert Timmerman, William L. Straube, Walter R. Bosch, Jeff Michalski, James M. Galvin pages 1235-1242 Abstract | Full Text | Full-Text PDF (359 KB)
Helical Tomotherapy Planning for Left-Sided Breast Cancer Patients With Positive Lymph Nodes: Comparison to Conventional Multiport Breast Technique S. Murty Goddu, Summer Chaudhari, Maria Mamalui-Hunter, Olga L. Pechenaya, David Pratt, Sasa Mutic, Imran Zoberi, Sam Jeswani, Simon N. Powell, Daniel A. Low pages 1243-1251 Abstract | Full Text | Full-Text PDF (688 KB)
Analysis of Salivary Flow and Dose–Volume Modeling of Complication Incidence in Patients With Head-and-Neck Cancer Receiving Intensity-Modulated Radiotherapy Simona Marzi, Giuseppe Iaccarino, Katia Pasciuti, Antonella Soriani, Marcello Benassi, Giorgio Arcangeli, Giuseppe Giovinazzo, Michaela Benassi, Laura Marucci pages 1252-1259 Abstract | Full Text | Full-Text PDF (318 KB)
A Comprehensive Assessment by Tumor Site of Patient Setup Using Daily MVCT Imaging From More Than 3,800 Helical Tomotherapy Treatments Leah K. Schubert, David C. Westerly, Wolfgang A. Tomé, Minesh P. Mehta, Emilie T. Soisson, Thomas R. Mackie, Mark A. Ritter, Deepak Khuntia, Paul M. Harari, Bhudatt R. Paliwal pages 1260-1269 Abstract | Full Text | Full-Text PDF (444 KB)
Gated Irradiation With Scanned Particle Beams Christoph Bert, Alexander Gemmel, Nami Saito, Eike Rietzel pages 1270-1275 Abstract | Full Text | Full-Text PDF (482 KB)
Impact of Intrafractional Bowel Gas Movement on Carbon Ion Beam Dose Distribution in Pancreatic Radiotherapy Motoki Kumagai, Ryusuke Hara, Shinichiro Mori, Takeshi Yanagi, Hiroshi Asakura, Riwa Kishimoto, Hirotoshi Kato, Shigeru Yamada, Susumu Kandatsu, Tadashi Kamada pages 1276-1281 Abstract | Full Text | Full-Text PDF (2409 KB)
Book Reviews
Treatment Methods for Early and Advanced Prostate Cancer Colleen A. Lawton page 1282 Full Text | Full-Text PDF (56 KB)
Textbook of Lung Cancer, 2nd edition James William Welsh page 1283 Full Text | Full-Text PDF (53 KB)
Letters to the Editor
Analysis of Interfraction Prostate Motion Using Megavoltage Cone Beam Computed Tomography by Bylund et al. (Int J Radiat Oncol Biol Phys 2008;72:949–956) Nandanuri Reddy, Dattatreyudu Nori, Christopher Lange page 1284 Full Text | Full-Text PDF (69 KB)
In Reply to Reddy et al. Kevin C. Bylund, John E. Bayouth, John M. Buatti pages 1284-1285 Full Text | Full-Text PDF (91 KB)
Potential Methodological Pitfalls in Assessing Quality of Life of Oral Cancer Patients After Low-Dose-Rate Interstitial Brachytherapy Xin-Biao Liao, Sen-Xiang Yan, Zhe Sun, Yu-Li Yi page 1285 Full Text | Full-Text PDF (56 KB)
In Reply to Dr. Lioa et al. Ryo-ichi Yoshimura, Hitoshi Shibuya page 1285 Full Text | Full-Text PDF (56 KB)
Universal Survival Curve and Single Fraction Equivalent Dose: Useful Tools in Understanding Potency of Ablative Radiotherapy: In Regard to Parks et al. (Int J Radiat Oncol Biol Phys 2008;72:1620–1621) Wolfgang A. Tomé page 1286 Full Text | Full-Text PDF (62 KB)
Volumetric Modulated Arc Therapy for Delivery of Prostate Radiotherapy: In Regard to Palma et al. (Int J Radiat Oncol Biol Phys 2008;70:996–1001) Piet Ost, Valérie Fonteyne, Wilfried De Neve, Werner De Gersem, Carlos De Wagter, Katrien Vandecasteele, Fréderic Duprez, Gert De Meerleer page 1286 Full Text | Full-Text PDF (55 KB)
In Reply to Dr. Ost and Colleagues David Palma, Vitali Moiseenko, Emily Vollans, Michael McKenzie, James Morris, Karl Otto page 1287 Full Text | Full-Text PDF (57 KB)
Is Smaller Better When It Comes to the Bladder?: In Regard to Stewart et al. (Int J Radiat Oncol Biol Phys 2008;72:843–848) Lauren Daniel Stegman page 1287 Full Text | Full-Text PDF (53 KB)
In Reply to Dr. Stegman Alexandra J. Stewart, Robert A. Cormack, Akila N. Viswanathan pages 1287-1288 Full Text | Full-Text PDF (59 KB)
Meetings page 1289 Full Text | Full-Text PDF (52 KB)
ASTRO News page 1290 Full Text | Full-Text PDF (56 KB)
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