| Editorials |
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Author(s) |
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Potential Interaction Between Sevelamer and Fat-Soluble Vitamins: A Hypothesis
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Paweena Susantitaphong,
Bertrand L. Jaber
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165-167
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Hyponatremia and Mortality in Patients With Cancer: The Devil Is in the Details
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Fadi Fakhouri,
Frédéric Lavainne,
Alexandre Karras
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168-169
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| In the Literature |
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Article Title |
Author(s) |
Pages |
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Lipid-Lowering Therapy in Individuals With CKD: Lessons Learned From SHARP
28 October 2011
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Ashish Upadhyay,
Daniel E. Weiner
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170-173
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Childhood Membranous Nephropathy and Dietary Antigens
21 October 2011
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Laurence H. Beck
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174-176
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| Original Investigations |
| Pathogenesis and Treatment of Kidney Disease |
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Article Title |
Author(s) |
Pages |
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Comparison of Calcium Acetate and Sevelamer on Vascular Function and Fibroblast Growth Factor 23 in CKD Patients: A Randomized Clinical Trial
05 December 2011
Background: Fibroblast growth factor 23 (FGF-23) is a marker of endothelial dysfunction and atherosclerotic complications in patients with chronic kidney disease (CKD). Because previous studies sugges...
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Mahmut Ilker Yilmaz,
Alper Sonmez,
Mutlu Saglam,
Halil Yaman,
Selim Kilic,
Tayfun Eyileten,
Kayser Caglar,
Yusuf Oguz,
Abdulgaffar Vural,
Mujdat Yenicesu,
Francesca Mallamaci,
Carmine Zoccali
et al.
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177-185
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Effect of Vitamin K2 Supplementation on Functional Vitamin K Deficiency in Hemodialysis Patients: A Randomized Trial
12 December 2011
Background: Vascular calcification is a predictor of cardiovascular morbidity and mortality. Hemodialysis patients experience severe vascular calcifications. Matrix Gla protein (MGP) is a central calc...
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Ralf Westenfeld,
Thilo Krueger,
Georg Schlieper,
Ellen C.M. Cranenburg,
Elke J. Magdeleyns,
Stephan Heidenreich,
Stefan Holzmann,
Cees Vermeer,
Willi Jahnen-Dechent,
Markus Ketteler,
Jürgen Floege,
Leon J. Schurgers
et al.
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186-195
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Serum Creatinine Measurement Immediately After Cardiac Surgery and Prediction of Acute Kidney Injury
04 October 2011
Background: After heart surgery, acute kidney injury (AKI) confers substantial long-term risk of death and chronic kidney disease. We hypothesized that small changes in serum creatinine (SCr) levels m...
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Julie Ho,
Martina Reslerova,
Brent Gali,
Peter W. Nickerson,
David N. Rush,
Manish M. Sood,
Joe Bueti,
Paul Komenda,
Edward Pascoe,
Rakesh C. Arora,
Claudio Rigatto
et al.
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196-201
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Periodontal Disease and Decreased Kidney Function in Japanese Elderly
17 October 2011
Background: Early detection of decreased kidney function can help prevent the progression of kidney disease to kidney failure and cardiovascular events. Potentially significant associations between ki...
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Masanori Iwasaki,
George W. Taylor,
Willem Nesse,
Arjan Vissink,
Akihiro Yoshihara,
Hideo Miyazaki
et al.
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202-209
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Genetic Association and Gene-Gene Interaction Analyses in African American Dialysis Patients With Nondiabetic Nephropathy
28 November 2011
Background: African Americans have increased susceptibility to nondiabetic nephropathy relative to European Americans. Study Design: Follow-up of a pooled genome-wide association study (GWAS) in Afric...
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Meredith A. Bostrom,
W.H. Linda Kao,
Man Li,
Hanna E. Abboud,
Sharon G. Adler,
Sudha K. Iyengar,
Paul L. Kimmel,
Robert L. Hanson,
Susanne B. Nicholas,
Rebekah S. Rasooly,
John R. Sedor,
Josef Coresh,
Orly F. Kohn,
David J. Leehey,
Denyse Thornley-Brown,
Erwin P. Bottinger,
Michael S. Lipkowitz,
Lucy A. Meoni,
Michael J. Klag,
Lingyi Lu,
Pamela J. Hicks,
Carl D. Langefeld,
Rulan S. Parekh,
Donald W. Bowden,
Barry I. Freedman,
Family Investigation of Nephropathy and Diabetes (FIND) Research Group
et al.
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210-221
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| Hypertension and Acid-Base/Electrolyte Disorders |
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Article Title |
Author(s) |
Pages |
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Hyponatremia in Hospitalized Cancer Patients and Its Impact on Clinical Outcomes
17 October 2011
Background: Hyponatremia is the most common electrolyte abnormality in clinical practice, yet little is known about its frequency in patients with cancer or its impact on their clinical outcomes. Stud...
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Simit M. Doshi,
Pankaj Shah,
Xiudong Lei,
Amit Lahoti,
Abdulla K. Salahudeen
et al.
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222-228
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Association of Filtered Sodium Load With Medullary Volumes and Medullary Hypoxia in Hypertensive African Americans as Compared With Whites
30 November 2011
Background: African Americans develop hypertension earlier with more target manifestations than whites despite having a higher glomerular filtration rate (GFR) for any level of serum creatinine. Study...
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Stephen C. Textor,
Monika L. Gloviczki,
Michael F. Flessner,
David A. Calhoun,
James Glockner,
Joseph P. Grande,
Michael A. McKusick,
Stephen S. Cha,
Lilach O. Lerman
et al.
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229-237
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| Dialysis |
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Author(s) |
Pages |
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Predialysis Serum Sodium Level, Dialysate Sodium, and Mortality in Maintenance Hemodialysis Patients: The Dialysis Outcomes and Practice Patterns Study (DOPPS)
26 September 2011
Background: Predialysis serum sodium concentrations recently have been linked to patient characteristics and outcomes in hemodialysis patients and may have implications for the dialysate sodium prescr...
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Manfred Hecking,
Angelo Karaboyas,
Rajiv Saran,
Ananda Sen,
Walter H. Hörl,
Ronald L. Pisoni,
Bruce M. Robinson,
Gere Sunder-Plassmann,
Friedrich K. Port
et al.
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238-248
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Appraising Stroke Risk in Maintenance Hemodialysis Patients: A Large Single-Center Cohort Study
26 September 2011
Background: Stroke incidence in hemodialysis patients is up to 10 times greater than in the general population and is associated with a worse prognosis. Factors influencing stroke risk by subtype and ...
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Albert Power,
Kakit Chan,
Seema K. Singh,
David Taube,
Neill Duncan
et al.
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249-257
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| Transplantation |
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Author(s) |
Pages |
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Progression of Coronary Artery Calcification and Thoracic Aorta Calcification in Kidney Transplant Recipients
26 September 2011
Background: Vascular calcification independently predicts cardiovascular disease, the major cause of death in kidney transplant recipients (KTRs). Longitudinal studies of vascular calcification in KTR...
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Céline Maréchal,
Emmanuel Coche,
Eric Goffin,
Anca Dragean,
Georg Schlieper,
Pauline Nguyen,
Jürgen Floege,
Nada Kanaan,
Olivier Devuyst,
Michel Jadoul
et al.
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258-269
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| Case Reports |
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Author(s) |
Pages |
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Polycystic Kidney Disease Presenting With Hypertension and Hypokalemia
03 October 2011
Hypokalemic hypertension is a common condition leading to the diagnosis of secondary hypertension. We report the case of a 60-year-old woman for whom the diagnosis of autosomal dominant polycystic kid...
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Kai Ming Chow,
Ronald Ching-Wan Ma,
Cheuk Chun Szeto,
Philip Kam-Tao Li
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270-272
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Recurrent Acute Kidney Injury Following Bath Salts Intoxication
28 November 2011
“Bath salts” are becoming recognized as a frequently abused and highly addictive substance that can be obtained legally in some areas. These agents contain stimulant compounds, such as methylenedioxop...
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Adedotun Adebamiro,
Mark A. Perazella
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273-275
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| Narrative Review |
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Author(s) |
Pages |
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Tuberous Sclerosis Complex–Associated Angiomyolipomas: Focus on mTOR Inhibition
30 November 2011
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder promoting the development of benign tumors in multiple organ systems, including the skin, brain, and kidneys. In contrast to asymptom...
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Klemens Budde,
Jens Gaedeke
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276-283
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| In Translation |
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Author(s) |
Pages |
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New Insights Into Human Minimal Change Disease: Lessons From Animal Models
05 October 2011
The pathogenesis of minimal change disease (MCD), considered to be the simplest form of nephrotic syndrome, has been one of the major unsolved mysteries in kidney disease. In this review, recent landm...
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Sumant S. Chugh,
Lionel C. Clement,
Camille Macé
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284-292
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| In Practice |
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Article Title |
Author(s) |
Pages |
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Managing Older Adults With CKD: Individualized Versus Disease-Based Approaches
22 December 2011
The last decade has seen the evolution and ongoing refinement of a disease-oriented approach to chronic kidney disease (CKD). Disease-oriented models of care assume a direct causal association between...
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C. Barrett Bowling,
Ann M. O'Hare
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293-302
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| Kidney Biopsy Teaching Case |
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Article Title |
Author(s) |
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Renal Sarcoidosis Presenting as Acute Kidney Injury With Granulomatous Interstitial Nephritis and Vasculitis
16 December 2011
Among the various renal manifestations of sarcoidosis, granulomatous inflammation confined to the tubulointerstitial compartment is the most commonly reported finding. We present the case of a 66-year...
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Varun Agrawal,
Giovanna M. Crisi,
Vivette D. D'Agati,
Benjamin J. Freda
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303-308
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| DOPPS Practice Monitor Update |
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Author(s) |
Pages |
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The DOPPS Practice Monitor for US Dialysis Care: Trends Through April 2011
12 December 2011
More than 380,000 people receive maintenance dialysis for the treatment of end-stage kidney failure in the United States. In 2008, Medicare expenditures for dialysis patients totaled $22 billion, or 4...
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Bruce M. Robinson,
Douglas S. Fuller,
Brian A. Bieber,
Marc N. Turenne,
Ronald L. Pisoni
et al.
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309-312
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Commentary on ‘The DOPPS Practice Monitor for US Dialysis Care: Trends Through April 2011’: No Surprises Yet
The initial announcement, finalization, and ultimate implementation of the end-stage renal disease prospective payment system (PPS), also called the expanded bundle, were accompanied by much angst in ...
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Wolfgang C. Winkelmayer,
Daniel E. Weiner
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312-314
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| Correspondence |
| Letters to the Editor |
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Article Title |
Author(s) |
Pages |
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Potassium and Metabolic Alkalosis
In the review on metabolic alkalosis by Gennari, the section on potassium depletion discusses the 2 studies in humans by Jones et al and Hernandez et al. In these studies, persons with normal intake o...
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Troels Ring
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315
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Metabolic Alkalosis Due to Hypercalcemia
Gennari presented an interesting classification on the causes of metabolic alkalosis. One remark, however, may be justified. Hypercalcemia should be included in the differential diagnosis of metabolic...
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Dinette E. Agterhuis,
Kenrick Berend
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315
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In Reply to ‘Potassium and Metabolic Alkalosis’ and ‘Metabolic Alkalosis due to Hypercalcemia’
I certainly agree with Dr Ring that the role of the kidney in acid-base disorders is not fully understood. I hope my review emphasized that point. Dr Ring, however, has misread what I wrote. I made no...
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F. John Gennari
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315-316
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Predialysis Care: Intertwined Roles of Nephrologists and Dietitians
Slinin et al provide an important analysis about the impact of dietitian care on mortality of incident hemodialysis patients. As the third table in their supplementary online material shows, the benef...
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Chia-Ter Chao
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316
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In Reply to 'Predialysis Care: Intertwined Roles of Nephrologists and Dietitians'
We thank Dr Chao for commenting on our article dealing with prehemodialysis care by dietitians, in which we reported an independent association between predialysis dietitian care for longer than 12 mo...
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Yelena Slinin,
Areef Ishani
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316-317
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What Dominates Living Donor Kidney Transplantation: Altruism or Loss of Dignity?
We were deeply moved by the altruistic kidney donations of Dr Levey and his colleague, as described in the recent perspective by Levey et al. The authors encourage transplant professionals and agencie...
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Kamyar Ghabili,
Mohammadali M. Shoja
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317
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In Reply to ‘What Dominates Living Donor Kidney Transplantation: Altruism or Loss of Dignity?’
In our recent perspective, as in our article 25 years ago, we focused on voluntary kidney donation from living kidney donors. Voluntarism is a core principle of the Declaration of Istanbul on Organ Tr...
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Gabriel Danovitch,
Susan Hou,
Andrew S. Levey
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317
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| Notice |
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Erratum regarding “Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial” (Am J Kidney Dis 2011; 58:729-736)
24 November 2011
In the article entitled “Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial” (Lewis et al, American Journal of Kidney Diseases 58(5):729-...
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318
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Masthead
The American Journal of Kidney Diseases (ISSN 0272-6386) is published monthly by Elsevier Inc., 360 Park Avenue South, New York, NY 10010-1710. Periodicals postage paid at New York, NY and additional ...
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A3
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Editorial Board
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A5-A6
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Contents
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A11-A15
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March Highlights
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A16
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Abbreviated Information for Authors
The American Journal of Kidney Diseases (AJKD) serves clinicians and scientists who treat and investigate kidney disease and associated conditions. AJKD is dedicated to providing high-quality, clinica...
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A21-A24
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Announcements
The Department of Nephrology, Dialysis and Transplantation of the San Bortolo Hospital in Vicenza, and the International Renal Research Institute of Vicenza will be holding the 30th International Vice...
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A26
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This Month in AJKD
See Doshi et al, pages 222-228; and Fakhouri et al, pages 168-169.
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A27-A28
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Bound by a Promise: Advance Directives and “Uninformed Consent”
“But it is too solemn—I think it is not right—to make a promise when I am ignorant what it will bind me to.” Dorothea Casaubon, from George Eliot's Middlemarch
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Joseph A. Abdelmalek,
Dena E. Rifkin
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A29-A31
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Quiz Page February 2012: Acute Kidney Injury in an Adolescent With a Family History of Autoimmune Disorders
A 15-year-old girl was admitted to the hospital with weakness, vomiting, abdominal pain, and darkening of the urine for several days. Type 1 diabetes mellitus was diagnosed 2 years previously, with po...
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Emma Allain-Launay,
Nicolas Blin,
Anne Moreau,
Gwenaëlle Roussey-Kesler
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A33-A35
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