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Cover 1
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OFC
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| Surgical Research Review |
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Error training: Missing link in surgical education
17 November 2011
People make mistakes. Human error is inevitable and must be anticipated, especially in environments where novices are developing new knowledge and skills. In medical education, faculty members are cha...
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Debra A. DaRosa,
Carla M. Pugh
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139-145
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| Clinical Review |
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Creating a learning healthcare system in surgery: Washington State’s Surgical Care and Outcomes Assessment Program (SCOAP) at 5 years
01 December 2011
There are increasing efforts towards improving the quality and safety of surgical care while decreasing the costs. In Washington state, there has been a regional and unique approach to surgical qualit...
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SCOAP Collaborative, The writing group for the SCOAP Collaborative,
Steve Kwon,
Michael Florence,
Peter Grigas,
Marc Horton,
Karen Horvath,
Morrie Johnson,
Gregory Jurkovich,
Wendy Klamp,
Kristin Peterson,
Terence Quigley,
William Raum,
Terry Rogers,
Richard Thirlby,
Ellen T. Farrokhi,
David R. Flum
et al.
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146-152
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| Surgical Outcome Research |
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Prevention of medical accidents caused by defective surgical instruments
26 September 2011
Background: The malfunctioning of surgical instruments may lead to serious medical accidents. Limited information is available on the risk of defective instruments. The purpose of these study is to de...
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Hiroshi Yasuhara,
Kazuhiko Fukatsu,
Takami Komatsu,
Toshihiko Obayashi,
Yuhei Saito,
Yushi Uetera
et al.
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153-161
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| Original Communications |
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Improving the clinical risk score: An analysis of molecular biomarkers in the era of modern chemotherapy for resectable hepatic colorectal cancer metastases
10 October 2011
Background: The prognostic relevance of variations in expression of specific tumor genes in colorectal cancer liver metastases (CRCLMs) in patients treated with resection and modern chemotherapy is no...
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Shishir K. Maithel,
Mithat Gönen,
Hiromichi Ito,
Ronald P. DeMatteo,
Peter J. Allen,
Yuman Fong,
Leslie H. Blumgart,
William R. Jarnagin,
Michael I. D'Angelica
et al.
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162-170
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Rates and patterns of death after surgery in the United States, 1996 and 2006
05 October 2011
Background: Nationwide rates and patterns of death after surgery are unknown. Methods: Using the Nationwide Inpatient Sample, we compared deaths within 30 days of admission for patients undergoing sur...
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Marcus E. Semel,
Stuart R. Lipsitz,
Luke M. Funk,
Angela M. Bader,
Thomas G. Weiser,
Atul A. Gawande
et al.
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171-182
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Use of omentum or falciform ligament does not decrease complications after pancreaticoduodenectomy: Nationwide survey of the Japanese Society of Pancreatic Surgery
10 October 2011
Background: Wrapping is thought to prevent pancreatic fistula and postoperative hemorrhage for pancreaticoduodenectomy (PD), and we analyzed whether omentum/falciform ligament wrapping decreases posto...
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Masaji Tani,
Manabu Kawai,
Seiko Hirono,
Takashi Hatori,
Toshihide Imaizumi,
Akimasa Nakao,
Shinichi Egawa,
Takehide Asano,
Takukazu Nagakawa,
Hiroki Yamaue
et al.
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183-191
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Prophylactic central lymph node dissection for clinically node-negative papillary thyroid microcarcinoma: Influence on serum thyroglobulin level, recurrence rate, and postoperative complications
19 April 2011
Background: In papillary thyroid microcarcinoma (PTMC), regional lymph node metastasis (LNM) is associated with a increased locoregional recurrence rate. Yet, prophylactic central lymph node dissectio...
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Yoon Kyoung So,
Min Young Seo,
Young-Ik Son
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192-198
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Lack of significant liver enzyme elevation and gallstones and/or sludge on ultrasound on day 1 of acute pancreatitis is associated with recurrence after cholecystectomy: A population-based study
05 October 2011
Background: In a population-based study, we examined recurrence rates of acute pancreatitis (AP) after cholecystectomy performed to prevent recurrences of AP. Methods: We abstracted data from medical ...
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Jan Trna,
Santhi Swaroop Vege,
Veronika Pribramska,
Suresh T. Chari,
Patrick S. Kamath,
Michael L. Kendrick,
Michael B. Farnell
et al.
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199-205
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Morphologic changes and prognosis of the respiratory tract epithelium in inhalation injury and their relationship with clinical manifestations
07 September 2011
Background: We set out to observe the morphologic changes and determine prognosis based on airway epithelial injury after inhalation injury of varying severity using a fiberbronchoscope and to explore...
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Li Ligen,
Yang Hongming,
Li Feng,
Shen Chuanan,
Hao Daifeng,
Tuo Xiaoye
et al.
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206-212
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The impact of CD4+CD25+ T cells in the tumor microenvironment of hepatocellular carcinoma
05 October 2011
Background: Hepatocellular carcinoma (HCC) is the most common liver cancer. Therapeutic results are usually unsatisfactory because liver tumors recur often. Immunologic factors may be related to the r...
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Wei-Chen Lee,
Ting-Jung Wu,
Hong-Shiue Chou,
Ming-Chin Yu,
Pao-Yueh Hsu,
Hsiu-Ying Hsu,
Chao-Ching Wang
et al.
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213-222
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The necessity of hepatic vein reconstruction after resection of cranial part of the liver and major hepatic veins in cirrhotic patients
23 December 2010
Background: The necessity of hepatic vein reconstruction (HVR) after resection of cranial part of the liver and major hepatic vein(s) in cirrhotic patients when residual liver is insufficient for a ma...
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Cheng-Chung Wu,
Cheng-Ming Peng,
Shao-Bin Cheng,
Dah-Cherng Yeh,
Wing-Yiu Lui,
Tse-Jia Liu,
Fang-Ku P’eng
et al.
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223-231
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Early cancer-related death after resection of hepatocellular carcinoma
23 December 2010
Background: Surgeons have attempted to prevent early cancer-related death after resection of hepatocellular carcinoma to identify risk factors associated with early death from hepatocellular carcinoma...
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Masamichi Moriguchi,
Tadatoshi Takayama,
Tokio Higaki,
Yuki Kimura,
Shintaro Yamazaki,
Hisashi Nakayama,
Takao Ohkubo,
Oamu Aramaki
et al.
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232-237
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Clinical impact of a macroscopically complete resection of colorectal cancer with peritoneal carcinomatosis
23 December 2010
Background: So far, few reports have focused on the clinicopathological features and patterns of recurrence after a complete resection of peritoneal carcinomatosis (PC) of colorectal origin. The purpo...
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Kenji Matsuda,
Tsukasa Hotta,
Katsunari Takifuji,
Motoki Yamamoto,
Toru Nasu,
Naoki Togo,
Masami Oka,
Katsuyoshi Tabuse,
Hiroki Yamaue
et al.
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238-244
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Outcomes of elective abdominal aortic aneurysm repair among the elderly: Endovascular versus open repair
19 January 2011
Background: National outcomes for elective abdominal aortic aneurysm (AAA) repair in elderly populations are needed. The purpose of this study was to analyze outcomes of endovascular (EVAR) and open s...
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Mehul V. Raval,
Mark K. Eskandari
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245-260
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Primary leiomyosarcoma of the inferior vena cava: A 2-institution analysis of outcomes
23 December 2010
Background: Approximately 300 cases of leiomyosarcoma of the inferior vena cava (IVC) have been reported in the literature to date. In this study, we combined the experience from 2 institutions to pro...
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Gary N. Mann,
Lisa V. Mann,
Edward A. Levine,
Perry Shen
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261-267
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Macrophage migration inhibitory factor is a potential inducer of endothelial progenitor cell mobilization after flap operation
03 January 2011
Background: Endothelial progenitor cells (EPCs) promote angiogenesis and play an important role in tissue revascularization and wound healing. Yet, the exact stimuli and mechanisms for the mobilizatio...
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Gerrit Grieb,
Andrzej Piatkowski,
David Simons,
Nives Hörmann,
Manfred Dewor,
Guy Steffens,
Jürgen Bernhagen,
N. Pallua
et al.
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268-277.e1
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Small intestine mucosal immune system response to injury and the impact of parenteral nutrition
13 December 2010
Background: Both humans and mice increase airway immunoglobulin A (IgA) after injury. This protective response is associated with TNF-α, IL-1β, and IL-6 airway increases and in mice is dependent upon ...
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Mark A. Jonker,
Joshua L. Hermsen,
Yoshifumi Sano,
Aaron F. Heneghan,
Jinggang Lan,
Kenneth A. Kudsk
et al.
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278-286
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Arginase inhibition promotes wound healing in mice
05 October 2011
Objective: Arginase plays important regulatory roles in polyamine, ornithine, and nitric oxide syntheses. However, its role in the healing process has not been delineated. In this study, we used a hig...
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Sandra L. Kavalukas,
Aarti R. Uzgare,
Trinity J. Bivalacqua,
Adrian Barbul
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287-295
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The angiogenic factor Del1 prevents apoptosis of endothelial cells through integrin binding
07 September 2011
Background: Del1 is a secreted protein that is expressed in the endothelium during development and can stimulate angiogenesis through integrin binding and signaling. We were interested in the specific...
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Zhen Wang,
Ramendra K. Kundu,
Michael T. Longaker,
Thomas Quertermous,
George P. Yang
et al.
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296-305
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Roles of thymidylate synthase and dihydropyrimidine dehydrogenase expression in blood as predictors of response to multimodal therapy in esophageal cancer
10 October 2011
Background: Thymidylate synthetase (TS) and dihydropyrimidine dehydrogenase (DPD) RNA expression in peripheral blood was examined as a noninvasive molecular predictor of response to neoadjuvant radioc...
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Jan Brabender,
Ralf Metzger,
Daniel Vallböhmer,
Frederike Ling,
Susanne Neiss,
Elfriede Bollschweiler,
Paul M. Schneider,
Arnulf H. Hölscher,
Peter P. Grimminger
et al.
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306-312
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Neutralization of interleukin-10 or transforming growth factor-β decreases the percentages of CD4+CD25+Foxp3+ regulatory T cells in septic mice, thereby leading to an improved survival
10 October 2011
Objectives: To investigate the role of CD4+CD25+Foxp3+ regulatory T cells (Tregs) in septic conditions, and to examine the potential of targeting them for the treatment of sepsis. Background: Sepsis-i...
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Shuhichi Hiraki,
Satoshi Ono,
Hironori Tsujimoto,
Manabu Kinoshita,
Risa Takahata,
Hiromi Miyazaki,
Daizoh Saitoh,
Kazuo Hase
et al.
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313-322
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Associations between promoter polymorphism -106A/G of interleukin-11 receptor alpha and papillary thyroid cancer in Korean population
10 October 2011
Background: The interleukin11 (IL11) and IL11 receptor alpha (IL11RA) are involved in cellular growth, differentiation, invasiveness, and tumor progression in several tumors. We investigated whether c...
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Young Gyu Eun,
Il Ho Shin,
Mi-Ja Kim,
Joo-Ho Chung,
Jeong Yoon Song,
Kee Hwan Kwon
et al.
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323-329
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Conditional and specific inhibition of NF-κB in mouse pancreatic β cells prevents cytokine-induced deleterious effects and improves islet survival posttransplant
10 October 2011
Background: Islets are susceptible to damage by proinflammatory cytokines via activation of transcription factor NF-κB. We hypothesized that inhibition of NF-κB activity will decrease cytokine–mediate...
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Jonathan S. Rink,
Xiaojuan Chen,
Xiaomin Zhang,
Dixon B. Kaufman
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330-339
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| Images in Surgery |
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A 1.3-cm carcinoid tumor of the minor duodenal papilla with superior mesenteric lymph node metastases
27 September 2010
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Tomohiro Maruyama,
Yoshio Shirai,
Jun Sakata,
Toshifumi Wakai,
Mitsuya Iwafuchi,
Katsuyoshi Hatakeyama
et al.
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340-341
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| Letter to the Editor |
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Hereditary diffuse gastric cancer: The always-forgotten Meckel’s diverticulum
The aim of prophylactic surgery is to remove as much of the at-risk tissue as possible to reduce the chances of developing cancer in the at risk tissue. This point is made clear by Pandalai et al in t...
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Valerie Bridoux,
Babak Kianifard,
Lilian Schwarz,
Francis Michot,
Jean-Jacques Tuech
et al.
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342
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| Erratum |
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Erratum
“A prospective study evaluating the accuracy of using combined clinical factors and candidate diagnostic markers to refine the accuracy of thyroid fine needle aspiration biopsy” by Aarti Mathur, Julie...
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343
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Contents
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A1-A5
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Information for authors
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A6-A8
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Information for readers
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A9
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