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Seminars in Radiation Oncology
Volume 20, Issue 4, Pages 215-288 (October 2010)
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Harnessing DNA Repair to Improve Radiotherapy Outcome
Edited by Robert G. Bristow MD, PhD, FRCPC

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Introduction: DNA Repair and Radiotherapy Targeting: An Overview free full text
Robert G. Bristow
pages 215-216
Full Text | Full-Text PDF (80 KB)


DNA Repair Targeting and Radiotherapy: A Focus on the Therapeutic Ratio
John Thoms, Robert G. Bristow
pages 217-222
Abstract | Full Text | Full-Text PDF (618 KB)


Use of γH2AX and Other Biomarkers of Double-Strand Breaks During Radiotherapy
Ali Sak, Martin Stuschke
pages 223-231
Abstract | Full Text | Full-Text PDF (1284 KB)


Single Nucleotide Polymorphisms of DNA Repair Genes as Predictors of Radioresponse
Matthew B. Parliament, David Murray
pages 232-240
Abstract | Full Text | Full-Text PDF (265 KB)


Targeting Base Excision Repair as a Sensitization Strategy in Radiotherapy
Conchita Vens, Adrian C. Begg
pages 241-249
Abstract | Full Text | Full-Text PDF (521 KB)


Targeting Nonhomologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization
Bipasha Mukherjee, Hak Choy, Chaitanya Nirodi, Sandeep Burma
pages 250-257
Abstract | Full Text | Full-Text PDF (752 KB)


The E2F1/Rb and p53/MDM2 Pathways in DNA Repair and Apoptosis: Understanding the Crosstalk to Develop Novel Strategies for Prostate Cancer Radiotherapy
Thirupandiyur Udayakumar, Mohammed M. Shareef, Dayssy A. Diaz, Mansoor M. Ahmed, Alan Pollack
pages 258-266
Abstract | Full Text | Full-Text PDF (739 KB)


Enhancing Radiotherapy Through a Greater Understanding of Homologous Recombination eExtra
Christopher A. Barker, Simon N. Powell
pages 267-273.e3
Abstract | Full Text | Full-Text PDF (536 KB)


Poly(ADP-Ribose) Polymerase Inhibition as a Model for Synthetic Lethality in Developing Radiation Oncology Targets
Anthony J. Chalmers, Mina Lakshman, Norman Chan, Robert G. Bristow
pages 274-281
Abstract | Full Text | Full-Text PDF (581 KB)


The Tumor Microenvironment and DNA Repair
Thomas J. Klein, Peter M. Glazer
pages 282-287
Abstract | Full Text | Full-Text PDF (229 KB)

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